| Year | Detail |
| 1840 |
Isaac Reckitt started a business. |
| 1848 |
The company was renamed to Isaac Reckitt and Son. |
| 1849 |
The company launched its first health product: Dietetic Arrowroot. |
| 1862 |
The company opens its first office at 40 King William Street, London. |
| 1888 |
Reckitt & Sons Ltd. becomes a public company. |
| 1905 |
Reckitt & Sons Ltd. launched the first liquid metal polish in U.K. |
| 1912 |
Reckitt & Sons Ltd. introduces a liquid metal polish for silverware. |
| 1924 |
The company launched window polish and Windolene. |
| 1932 |
Reckitt & Sons Ltd. acquired Harpic toilet cleaner from Harry Pickup. |
| 1933 |
The company launched Dettol, the first pharmaceutical product introduced into the medical profession. |
| 1938 |
Reckitt & Colman Ltd. was formed to integrate the household product business with the food business. |
| 1960 |
The company has entered into the air freshener market. |
| 1970 |
The company acquired Gaviscon. |
| 1985 |
Reckitt & Colman acquired Airwick Industries to strengthen its portfolio across haircare products. |
| 1999 |
Reckitt & Colman merged with Benckiser NV. |
| 2006 |
Reckitt Benckiser acquires Boots Healthcare International. |
| 2013 |
The company has acquired most Latin American Healthcare brands, such as Bristol Myers-Squibb, Naldecon, Luftal, Dermodex, Tempra, Picot, and Graneodin in Mexico. |
| 2017 |
The company has acquired two infant nutrition brands: Enfa and Nutramigen. |
| 2020 |
The company launched Reckitt Global Hygiene Institute to fill the gaps regarding hygiene, behaviors, and solutions. |
| 2021 |
The company purchased Biofreeze, a pain relief brand from Performance Health in the U.S. |