August 08, 2018
WELLESLEY, Mass., Aug 8, 2018–Exciting developments in the world of immunotherapy are helping to drive incredible growth of the chimeric antigen receptor cell therapy market, according to a report by BCC Research.
The industry is expected to see a compound annual growth rate (CAGR) of 44.1% through 2023, when it could be worth $2.9 billion, according to the report Chimeric Antigen Receptor (CAR)-T Cell Therapy: Current Research and Development Status.
Major players in the market include 3S Bio, Ambrx, Batu Biologics, Carsgen Therapeutics, Editas Medicine, Fate Therapeutics, GlaxoSmithKline, F. Hoffman La Roche, Immunocore, Juno Therapeutics, JW Biotechnology, Lokon Pharma, Merck, Novartis, Oxford BioMedica, Partikula, Regen Biopharma, Sangamo Therapeutics, Takara Bio and Ziopharm Oncology.
“For years, the foundations of cancer treatment were surgery, chemotherapy and radiation therapy,” said BCC Research analyst and report author Paul Taylor. “But over the past several years, immunotherapy—therapies that enlist and strengthen the power of a patient’s immune system to attack tumors—has emerged as what many in the cancer community now call the ‘fifth pillar’ of cancer treatment.”
Antigen Loss Relapse and On/Off Tumor Toxicity Among Market Challenges
Although the market has overcome a number of critical obstacles in recent years, several looming challenges remain, notes Taylor. Chief among them are antigen loss relapse, on-target/off-target toxicity resulting from the recognition of healthy tissues by CAR-T cells, and less efficacy in solid tumors due to hostile tumor microenvironments.
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Current Research & Developments Status of Chimeric Antigen Receptor (CAR) T-Cell Therapy( BIO162A )
Publish Date: Jul 2018
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