The Global Market for Pain Management Drugs and Devices

October 13, 2009

SUMMARY FIGURE

WORLDWIDE PAIN MANAGEMENT PHARMACEUTICALS AND DEVICES MARKET AT MANUFACTURERS’ SALES LEVELS, 2006-2013

$ MILLIONS

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Source: BCC Research

• Undertreatment issues
• Professional issues
• Managed-care pain issues
• Trends in new therapies and product pipelines
• Generic participation
• Pain research
• Drug delivery
• Patent expirations
• Developments in breakthrough pain
• New regulatory requirements
• Demographic trends
• Incidence and prevalence trends.

• Systems and imaging – Using imaging, investigators can now see that pain activates at least three or four key areas of the brain’s cortex Channels – The possibility now exists for developing new classes of drugs, including pain cocktails that would act at the site of channel activity (Continued)
• Trophic factors – Investigators have observed that an over-accumulation of certain trophic factors in the nerve cells of animals results in heightened pain sensitivity, and that some receptors found on cells respond to trophic factors and interact with each other; these receptors may provide targets for new pain therapies
• Molecular genetics – The dramatic changes that occur with injury and persistent pain underscore that chronic pain should be considered a disease of the nervous system, not just prolonged acute pain or a symptom of an injury; thus, scientists hope that therapies directed at preventing the long-term changes that occur in the nervous system will prevent the development of chronic pain conditions
• Neurotransmitters – Using sophisticated imaging technologies, investigators can now visualize what is happening chemically in the spinal cord. From this work, new therapies may emerge that can help reduce or obliterate severe or chronic pain.

One objective of investigators working to develop the future generation of pain medications is to take full advantage of the body’s pain “switching center” by formulating compounds that will prevent pain signals from being amplified or stop them altogether. Blocking or interrupting pain signals, especially when there is no injury or trauma to tissue, is an important goal in the development of pain medications. An increased understanding of the basic mechanisms of pain will have profound implications for the development of future medicines.

The Global Market for Pain Management Drugs and Devices( HLC026C )
Publish Date: Aug 2009    

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