| Year | Detail |
| 1980 |
Amgen was founded as Applied Molecular Genetics Inc. as the brainchild of venture capitalists William K. Bowes and associates. |
| 1984 |
Kirin and Amgen formed a joint venture, Kirin-Amgen, to commercialize erythropoietin worldwide. |
| 1985 |
Applied Molecular Genetics Inc. developed the company's second blockbuster drug, NEUPOGEN (filgrastim). |
| 1989 |
FDA approved EPOGEN (epoetin alfa), EPOGEN is named Product of the Year, by Fortune magazine. In the same year it established its European headquarters in Lucerne, Switzerland. |
| 1993 |
The company has opened its Puerto Rico facility, which has become Amgen's flagship manufacturing site with over 1.7 million square feet of space. |
| 1998 |
FDA approves Enbrel (etanercept). |
| 1999 |
Amgen Scientists identify and clone osteoprotegerin (OPG). |
| 2001 |
Amgen's Cambridge, Massachusetts research center opens and the same year Aranesp (darbepoetin alfa) is approved by the FDA. |
| 2001 |
Amgen and NASA team up to study Amgen's investigational treatment, osteoprotegerin (OPG), on the space shuttle Endeavour. |
| 2002 |
The company acquires Immunex, the developer of ENBREL (etanercept), along with a manufacturing plant in Rhode Island and in the same year Neulasta (pegfilgrastim) is approved by the FDA. |
| 2004 |
Amgen acquired Tularik, establishing a strong presence in South San Francisco, and in the same year, Sensipar (cinacalcet) was approved by the FDA. |
| 2010 |
Prolia (denosumab) and XGEVA (denosumab) are approved by the FDA |
| 2011 |
Amgen, CDC, and CDC Foundation partner to improve infection control for cancer patients. |
| 2011 |
The company acquired a manufacturing facility near Dublin, Ireland, and acquired the company BioVex, developers of talimogene laherparepvec, and expanded in Brazil, including the acquisition of Bergamo, a privately held Brazilian pharmaceutical company. |
| 2012 |
Amgen acquired deCODE Genetics, a global company in human genetics, and Amgen Teach launched in Europe. |
| 2013 |
The company Amgen Astellas BioPharma K.K. alliance forms in Japan and Amgen-Betta Pharmaceuticals joint venture is established in China and it also acquired Onyx Pharmaceuticals, developers of Kyprolis® (carfilzomib) for Injection. |
| 2014 |
Amgen's Asia Research and Development Center opens at ShanghaiTech University in China. |
| 2015 |
Amgen's first commercial chemical synthesis manufacturing facility opens in Singapore and Corlanor (ivabradine), IMLYGIC (talimogene laherparepvec) and Repatha (evolocumab) are approved by the FDA. |
| 2017 |
The company has opened its Amgen Capability Center (ACC) in Tampa, Florida and also launched the ENBREL (etanercept) Mini single-dose prefilled cartridge with AutoTouch Reusable Autoinjector that is ergonomically designed for patients. |
| 2018 |
Amgen established its new next-generation biomanufacturing plant at its West Greenwich, Rhode Island campus. |
| 2019 |
It has completed the acquisition of Otezla (apremilast). |
| 2020 |
Amgen announced a strategic collaboration with BeiGene to expand its oncology presence in China and established a Wholly-Owned Affiliate In Japan. |