AXOSIM

AxoSim’s revolutionary NerveSim technology is the only in vitro model with high levels of Schwann cell myelination and human-relevant electrical and structural metrics, which are considered a powerful tool for human translation. The platform grows living human cells in a proprietary 3D environment to mimic nerve tissue in both form and function. Using the most clinically relevant readouts for peripheral neurotoxicity, nerve conduction, and histomorphometry, AxoSim delivers in vivo results on an innovative, bioengineered in vitro platform.

It enables human-relevant oligodendrocyte myelination for neurotoxicity and neurodegenerative disease applications. The platform recreates a biomimetic 3D environment comprising neurons, astrocytes, and oligodendrocytes.

It is an in vitro model of the central nervous system (CNS) consisting of neurons, astrocytes, and microglia. The platform delivers CNS electrophysiology and spontaneous neural network activity.