| Year | Detail |
| 1929 |
Dr. Henri Beaufour founded the Beaufour Laboratories in Dreux. |
| 1975 |
Laboratoires Beaufour created a subsidiary and began to internationalize its activities. |
| 1983 |
The group created the Fondation Ipsen under the aegis of the Fondation de France to encourage exchanges between scientists in life sciences. |
| 1994 |
The group launched Dysport (type A botulinum toxin for treating muscle spasms) after acquiring the British company Speywood (then called Porton International). |
| 1995 |
The group launched Somatuline, which treats hypersecretion of growth hormones (acromegaly) in neuroendocrine tumors. |
| 2003 |
The company changed its name to Ipsen. |
| 2007 |
The company partnered with Galderma to produce botulinum toxin type-A products in aesthetic medicine. |
| 2011 |
Ipsen announced a new strategy focusing on several areas, including a refocus on specialty medicine, research and development, and international development. |
| 2013 |
Ipsen acquired Syntaxin, a leader in the engineering of recombinant botulinum toxin, for $37 million. The acquisition was seen as a way for Ipsen to strengthen its position in botulinum toxin-based therapies. |
| 2019 |
Ipsen acquired Clementia Pharmaceuticals, which specializes in rare bone diseases. Clementia brought a drug candidate, palovarotene, to Ipsen for a rare genetic disease, fibrodysplasia ossificans progressiva (FOP). |
| 2022 |
Ipsen announced the proposed sale of the Consumer HealthCare (CHC) division after entering into exclusive negotiations with the French laboratory Mayoly Spindler. |
| 2022 |
Ipsen-acquired Tazverik (tazemetostat), a first-in-class, chemotherapy-free EZH2a inhibitor for adults with relapsed or refractory Follicular Lymphoma (FL), was granted Accelerated Approval by the U.S. Food and Drug Administration (FDA) in 2020. |
| 2023 |
Ipsen acquired rare liver disease specialist Albireo, bringing into its portfolio Bylvay (odevixibat), a non-systemic ileal bile acid transport inhibitor for the treatment of pediatric patients with pruritus in progressive familial intrahepatic cholestasis (PFIC). |