| Year | Detail |
| 1849 |
A family business for optics was founded in Wetzlar, Germany. |
| 1853 |
Foundation of the Bausch & Lomb Instruments Division in USA. |
| 1869 |
Ernst Leitz takes over "Optical Institute" and changes the company name into “Ernst Leitz”. |
| 1872 |
Precision Engineering company R. Jung founded in Heidelberg. |
| 1921 |
Foundation of the optical company Wild Heerbrugg in Switzerland. |
| 1925 |
First Polarizing Microscope introduced. |
| 1932 |
Incident Light Fluorescence Microscopy introduced. |
| 1981 |
Foundation of the Wild Leitz group. |
| 1986 |
Merger of Ernst Leitz and Wild Heerbrugg to form the Wild Leitz Group. |
| 1990 |
Merger of Wild Leitz, Cambridge Instruments, Reichert & Jung and Bausch & Lomb to form the Leica Group. |
| 1993 |
1st Joint Venture Opening of the Leica group in China for specimen preparation. |
| 1998 |
The Business Divisions of the Leica Group, Leica Camera, Leica Microsystems and Leica Geosystems become three independent companies. |
| 2004 |
First Super-Resolution Confocal (4Pi) Microscope. |
| 2007 |
The Leica Biosystems division was formed. |
| 2008 |
Leica Microsystems becomes a founder partner of the European Molecular Biology Laboratory (EMBL) Advanced Training Centre in Heidelberg Germany. |
| 2010 |
Kavo Dental and Leica Microsystems partnered for dental microscopes. |
| 2017 |
Launched new SP8 DIVE system. |
| 2018 |
Launched the PROvido multidisciplinary microscope. |