ACCURAGEN HOLDINGS
Company Snapshot
Founded: 2013
Entity Type: Private
Region: U.S.
Headquarter: California, U.S.
Key Geographics: North America
Corporate Address: 2720 Zanker Rd, Suite 100, San Jose, California 95134 U.S. www.accuragen.com
Company Overview
AccuraGen Holdings, founded in 2013, is developing a liquid biopsy technology platform called Firefly, which uses NGS for analysis. The platform is able to identify low-frequency mutations in cfDNA by creating DNA concatemers (long, continuous DNA polymer that contains multiple copies of the same DNA sequence linked in series).
The technology uses rolling circle amplification in which cfDNA is denatured to produce ssDNA fragments. This DNA is amplified via rolling circle amplification (DNA is circularized by ligation reaction). This circularized DNA is then amplified to form a concatemer with multiple tandem repeats. After this step, target enrichment and sequencing are performed.
Company's Business Segments
- Liquid Biopsy : AccuraGen has pioneered the Development of Liquid Biopsy Technology to facilitate Personalized Cancer Treatment.
Applications/End User Industries
- Biotechnology Research
- Cancer Detection
- Liquid Biospy
- Clinal Management
- Drug Discovery
- Healthcare
- Drug Validation
