Next-generation Sequencing: Emerging Clinical Applications and Global Markets

Report Code: BIO126E

Publish Date: Feb 2024

Publisher: BCC Publishing

Category: Cell Biology

Download Report Overview

Single User License: $4650

Member Price: FREE

EXPLORE OFFERS

Explore Our Services

Already a member? Login to access this report free.

Report Highlights

The global market for clinical applications of next-generation sequencing is estimated to increase from $21.9 billion in 2023 to reach $52.9 billion by 2028, at a compound annual growth rate (CAGR) of 19.3% from 2023 through 2028.

Report Includes

  • 41 data tables and 237 additional tables
  • An overview of the global market for emerging clinical applications of next-generation sequencing
  • Analysis of global market trends, featuring historical revenue data for 2020 to 2022, estimates for 2023, as well as forecasts for 2028, including projections of compound annual growth rates (CAGRs) through 2028
  • Evaluation of the current market size and revenue growth prospects, accompanied by a market share analysis by disease indication, test complexity, test purpose, application and geographic region
  • Discussion of market opportunities for clinical NGS products, clinical applications, industry structure, regulatory scenarios and use of NGS-based diagnostics and technologies
  • Coverage of genome mapping programs, technological advances and innovations in NGS platforms, and the Ion Torrent Genexus System from Thermo Fisher Scientific and the Magnis NGS Prep System lfrom Agilent Technologies Inc
  • Description of NGS-oriented tests such as non-invasive prenatal testing (NIPT) and pre-implantation genetic testing (PGT), and a discussion of their advantages
  • Market share analysis of the key companies and a look at their proprietary technologies, strategic alliances and other key market strategies, plus a patent analysis
  • Profiles of the leading players, including Illumina Inc., Thermo Fisher Scientific Inc., QIAGEN, Agilent Technologies Inc., and BGI Genomics

Report Scope

The scope of the report includes clinical NGS technologies, applications, industries, initiatives, patents, and companies. The markets for NGS-based diagnostics are given for the years 2020, 2021, 2022, 2023 and 2028.

This report reviews the main sequencing technologies and explains why genetic variation is important in clinical testing. It then discusses some of the significant research initiatives that impact clinical NGS applications. Liquid biopsy formats are discussed. The main market driving forces are also discussed.

The report examines the markets by test complexity, clinical indication and test purpose. Test complexity refers to the plex level (i.e., the number of genetic markers that can be analyzed within a sample) and coverage (e.g., the extent to which the genome is covered) of the test. Examining the market by test complexity provides valuable insight into which products (e.g., sample preparation, NGS instrument, informatics, etc.) will be in demand in the future.

The report provides market data and forecasts for NGS diagnostics by specific applications, including those for oncology, cardiovascular diseases, clinical microbiology/infectious diseases, Mendelian disorders, metabolic/immune disorders, neurological disorders, reproductive health, and transplant medicine.

Specific geographic markets are discussed, namely North America, Europe, Asia-Pacific, and the Rest of the World.

Industry sectors analyzed include DNA sequencing instruments; long-read sequencing; sequencing informatics; target enrichment; CTC capture and detection; liquid biopsy; cancer screening/early detection; direct-to-consumer testing; and noninvasive prenatal testing.

More than 100 companies in the clinical NGS industry are profiled in this report.

BCC Research also provides a summary of the recent, primary industry acquisitions and strategic alliances, including key alliance trends.

Report Synopsis

Report Metrics Details
Base year considered 2022
Forecast period considered 2023-2028
Base year market size $18.4 billion
Market size forecast $52.9 billion
Growth rate CAGR of 19.3% for the forecast period of 2023-2028
Units considered $ Millions
Segments covered Disease Class, Test Complexity, Analysis Type, and Geographic Region
Regions covered North America, Europe, Asia-Pacific, and Rest of the World
Countries covered Austria, Belgium, Czech Republic, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Ireland, Iceland, Italy, Luxembourg, Netherlands, Norway, Poland, Portugal, Romania, Spain, Switzerland, Turkey, UK, Sweden, Australia, China, India, Japan, Malaysia, New Zealand, Philippines, Singapore, Taiwan, Thailand, South Korea, Argentina, Brazil, Chile, Israel, Kuwait, Russia, Saudi Arabia, South Africa, UAE
Key Market Drivers
  • Growing demand for precision medicine.
  • Emergence of tissue-agnostic drug labels
  • Increasing endorsement of liquid biopsy-based diagnostics from key industry stakeholders
  • Emergence of several high market potential (“mega”) applications
Companies studied
AGILENT TECHNOLOGIES INC. BGI GENOMICS CO. LTD
ILLUMINA INC.QIAGEN
THERMO FISHER SCIENTIFIC INC.ACCURAGEN HOLDINGS
ADAPTIVE BIOTECHNOLOGIES ALCEN
AMBRY GENETICSAMOY DIAGNOSTICS CO. LTD.
ANGLE PLCAPOSTLE SCIENCES
ARCEDI BIOTECH APSARMONICA TECHNOLOGIES INC.
ARUP LABORATORIESASURAGEN INC.
BAYLOR GENETICSBD
BERRY GENOMICS BEIJINGBIOCAPTIVA LTD.
BIOCEPT INC.BIODESIX
BIOLIDICS LTD.BIOFLUIDICA
BIOLOGICAL DYNAMICSBIOMODAL
BIONANO GENOMICSBIO-RAD LABORATORIES INC.
BIO-TECHNEC2I GENOMICS
CAPIO BIOSCIENCESCAREDX INC.
CARIS LIFE SCIENCESCEGAT GMBH
CELL MICROSYSTEMSCENTRILLION GENOMICS TECHNOLOGIES
CLARET BIOSCIENCECLEAR NOTE HEALTH
CLINICAL GENOMICS TECHNOLOGIESCYCLOMICS
CYGNUS BIOSCIENCES CO. LTD. (SINA BIOTECH (BEIJING) CO. LTD.)DANAHER CORP.
DANTE LABSDATAR CANCER GENETICS
DELFI DIAGNOSTICSDIACARTA
DIAGNOLOGIX LLCDIAGNOMICS INC.
DIAMIR BIODNALYTICS
DNANEXUS INC.EARLYDIAGNOSTICS
EONE-DIAGNOMICS GENOME CENTER CO. LTD.EPIC SCIENCES
EPIGENOMICS AGEUROFINS GENOMICS
EVERLYWELL INC.EXACT SCIENCES CORP.
EXOPERTEXOSOMICS SPA
EZLIFE BIOFABRIC GENOMICS INC.
F. HOFFMANN-LA ROCHE LTD.FLUXION BIOSCIENCES INC.
FREENOME HOLDINGS INC.FULGENT GENETICS
FULL GENOMES CORP.GENE BY GENE LTD.
GENEDX LLCGENESEQ BIOSCIENCES
GENOMONCOLOGY LLCGENOSABER
GRAILGUARDANT HEALTH
HELIO GENOMICSHELIX INC.
HTG MOLECULAR DIAGNOSTICS INC.IMAGIA CANEXIA HEALTH
INCELLDX INC.INEX INNOVATE PRIVATE LTD.
INOVIQINTERPACE BIOSCIENCES INC.
INVITAE CORP.INVIVOSCRIBE INC.
JABREHOO MED TECH CO. LTD.JBS SCIENCE
JUMPCODE GENOMICS INC.KONINKLIJKE PHILIPS N.V.
LABGENOMICS CO. LTD.LABORATORY CORPORATION OF AMERICA HOLDINGS
LIQUID BIOPSY LABSLUCENCE HEALTH INC.
LUNGLIFE AI INC.MACROGEN INC.
MAPMYGENOMEMDXHEALTH INC.
MEDGENOMEMEDICOVER GENETICS
MENARINI SILICON BIOSYSTEMSMERCK KGAA
MICAREO RARE CELL DIAGNOSTICSMICRONOMA INC.
MIR SCIENTIFICMUTANTDX
MYRIAD GENETICS INC.NANOSTRING TECHNOLOGIES INC.
NATERA INC.NEBULA GENOMICS
NEOGENOMICS LABORATORIESNEW ENGLAND BIOLABS
NEW HORIZON HEALTH LTD.NOVIGENIX SA
NOVOGENE CO. LTD.NRICHDX INC.
NUPROBE INC.NX PRENATAL INC.
ONCIMMUNE HOLDINGS PLCONCOCYTE CORP.
PANGAEA ONCOLOGYONCODNA
OPKO HEALTHORCHID
OXFORD NANOPORE TECHNOLOGIES PLC.PACBIO
PERSONAL GENOME DIAGNOSTICS INC.PERSONALIS INC.
PHASE SCIENTIFICPIERIANDX
PREDICINEPRENETICS GROUP
QCDX LLCQUANTAPORE
QUANTGENE INC.QUANTUMDX GROUP LTD.
QUEST DIAGNOSTICS INC.RARECELLS INC.
RAVGENREAL TIME GENOMICS
RESOLUTION BIOSCIENCE INC.SAGA DIAGNOSTICS AB
SANO GENETICSSCREENCELL
SEEKIN INC.SEQUENCING.COM
SEVEN BRIDGES GENOMICS (VELSERA)SINGLE TECHNOLOGIES
SMARTCATCHSTAGEZERO LIFE SCIENCES. LTD.
STRANDSTRATA ONCOLOGY
SYAPSE INC.SYSMEX INOSTICS INC.
TAKARA BIO INC.TELEXOS GMBH
TWINSTRAND BIOSCIENCES INC.TWIST BIOSCIENCE
UNCHAINED LABSUNIVERSAL DX
VELA DIAGNOSTICSVERACYTE
VOLITIONRXVORTEX BIOSCIENCES
YOURGENE HEALTH YIKON GENOMICS (SUZHOU) CO. LTD.
Need a custom data table, graph, region, segment, companies or complete report? CUSTOMIZE NOW

Frequently Asked Questions (FAQs)

The global Next-generation sequencing market in clinical application was valued at $18.4 billion in 2022 and will reach $52.9 billion by 2028. It is expected to witness a CAGR of 19.3% from 2023 to 2028.
The global market for Next-generation sequencing in clinical application is witnessing intrinsic growth owing to improvements to NGS test workflow technologies, increasing emphasis on genomic characterization of tumors, limitations of tissue biopsy, growing use of precision medicine to treat diseases, and penetration of clinical sequencing into applications with large potential markets.
The Next-generation sequencing market in clinical application is segmented based on disease type, test complexity, purpose of tests, and region.
The oncology segment will dominate the market in 2028.
North America holds the highest share of the market.

Analyst Credentials

BCC Research Team possesses expertise and experience in life and physical science domains. They specialize in offering valuable business insights, including industry analysis, competitor intelligence, strategic and financial analysis, and opportunity assessment. The team has in-depth knowledge of various sectors, including healthcare, biotechnology, pharmaceuticals, IT, automation, advanced materials, and energy. They are proficient in qualitative and quantitative market intelligence providing clients with actionable insights. With a vast understanding of the competitive landscape, the team can support clients in making data-driven decisions to help them achieve a competitive edge in their respective markets.

Consulting Editor’s Credentials

Dr. Marianna Tcherpakov has more than 10 years of experience as a bench scientist specializing in the areas of biochemistry, cell biology, assay development, antibody and drug manufacturing. She has authored several scientific publications in peer review journals. In the last 10 years, Marianna worked as a business development professional in CRO/CDMO industry. She is familiar with pharmaceutical and biotech landscape, trends and potential future developments in industry.

Let us assist you! Our analysts are ready to tailor this report to your specific need. Talk to Our Analyst

Table of Contents

All reports provided in PDF format. For shared licensing options (5+ Users), please call a representative at (+1) 781-489-7301 or contact us at info@bccresearch.com
Title/Chapter NamePagesMember Price
Full Report: Next-generation Sequencing: Emerging Clinical Applications and Global Markets492Free
Chapter- 1: Introduction5Free
Chapter- 2: Summary and Highlights4Free
Chapter- 3: Overview7Free
Chapter- 4: Technology Background31Free
Chapter- 5: Clinical NGS Initiatives and Emerging Technologies21Free
Chapter- 6: Clinical NGS Applications15Free
Chapter- 7: Clinical NGS Industry46Free
Chapter- 8: ESG Development8Free
Chapter- 9: Acquisitions and Strategic Alliances30Free
Chapter- 10: Clinical NGS Markets104Free
Chapter- 11: Patent Review13Free
Chapter- 12: Company Profiles208Free
Published - Jun-2021| Analyst - John Bergin| Code - BIO126D

Report Highlights

The global market for clinical next-generation sequencing (NGS) should grow from $5.9 billion in 2020 to $22.9 billion by 2025 with a compound annual growth rate (CAGR) of 31.4% for the period of 2020-2025.

Report Includes

  • 29 data tables and 73 additional tables
  • An updated review of the global market for emerging clinical applications of the next-generation sequencing (NGS) based diagnostics and related technologies
  • Analyses of the global market trends, with data from 2019-2020, and projections of compound annual growth rates (CAGRs) through 2025
  • Discussion of market opportunities for clinical NGS products, clinical applications, industry structure, regulatory scenario, and penetration of NGS-based diagnostics and technologies within the industry
  • Estimation of the current market size and revenue forecasts for the global NGS diagnostic markets, and corresponding market share analysis by disease indication, test complexity, test purpose, application and geographic region
  • Evaluation of the key NGS workflow portions of the industry (e.g., sequencing instruments, pre-sequencing target preparation and capture, and post-sequencing data analysis) and the main clinical indications where NGS will capture significant market share by 2025
  • Assessment of main sequencing technologies and explanation of the importance of genetic variation in clinical testing as well as some of the significant research initiatives affecting clinical NGS applications
  • A summary of the major acquisitions and strategic alliances in the clinical NGS industry from January 2019 through April 2021, including key alliance trends
  • Patent review and significant allotments of the U.S. patents in the liquid biopsy industry
  • Company profiles of the major market players, including Agilent Technologies Inc., Becton, Dickinson and Co. (BD), Koninklijke Philips N.V., Merck KGaA, Novogene Co. Ltd., Oxford Nanopore Technologies Ltd., Qiagen NV, Roche Holding AG,  and Thermo Fisher Scientific Inc.
Published - Jun-2017| Analyst - John Bergin| Code - BIO126C

Report Highlights

The global clinical next-generation sequencing (NGS) market reached $2.7 billion in 2016. This market is expected to grow at a compound annual growth rate (CAGR) of 27%, from nearly $3.2 billion in 2017 to $10.5 billion by 2022.

Report Includes

  • An overview of the global market for next-generation sequencing and its emerging clinical applications.
  • Analyses of global market trends, with data from 2016, estimates for 2017, and projections of compound annual growth rates (CAGRs) through 2022.
  • Examination of the sequencing industry structure for key market segments.
  • Discussion covering the strategies employed by the main companies in the market.
  • Comprehensive company profiles of major players in the field.
Published - Jun-2015| Analyst - John Bergin| Code - BIO126B

Report Highlights

The global clinical next-generation sequencing (NGS) market was valued at $886.1 million in 2014. This market is expected to grow at a compound annual growth rate (CAGR) of 31.3%, from $997.1 million in 2015 to nearly $3.9 billion by 2020.

Report Includes

  • An overview of the global market for next-generation sequencing and its emerging clinical applications.
  • Analyses of global market trends, with data from 2014, estimates for 2015, and projections of CAGRs through 2020.
  • Examination of the sequencing industry structure for key market segments.
  • Discussion covering the strategies employed by the main companies in the market.
  • Comprehensive company profiles of major players in the field.
Published - Jul-2013| Analyst - John Bergin| Code - BIO126A

Report Highlights

The next generation sequencing market reached $231.7 million in 2012. The market is expected to reach $510.7 million in 2013 and $7.6 billion in 2018 for a compound annual growth rate (CAGR) of 71.6%.

Report Includes

  • An overview of the global market for next-generation sequencing and its emerging clinical applications
  • Analyses of global market trends, with data from 2012, estimates for 2013, and projections of compound annual growth rates (CAGRs) through 2018
  • Examination of the sequencing industry structure for the key market segments, as well as strategic alliances and acquisitions, as well as evaluations of sequencing patents
  • Discussion of the strategies of the main companies in the market
  • Comprehensive company profiles of major players in the field

Related Reports

Global DNA Sequencing: Research, Applied and Clinical Markets

Published - Dec 2024 | Publisher - BCC Publishing | Code - BIO045J

The global market for DNA sequencing is expected to grow from $14.8 billion in 2024 and is projected to reach $34.8 billion by the end of 2029, at a compound annual growth rate (CAGR) of 18.6% during the forecast period of 2024 to 2029.

Rare Disease Diagnostics: Technologies and Global Markets

Published - Dec 2024 | Publisher - BCC Publishing | Code - PHM227B

The global market for rare disease diagnostics is estimated to increase from $21.6 billion in 2024 to reach $34.7 billion by 2029, at a compound annual growth rate (CAGR) of 9.9% from 2024 through 2029.

Direct-to-Consumer Genetic Testing: Global Markets and Technologies

Published - Nov 2024 | Publisher - Gundreddy Gopinadh | Code - MDS008B

The global market for DTC genetic testing is expected to grow from $2.3 billion in 2024 and is projected to reach $3.7 billion by the end of 2029, at a compound annual growth rate (CAGR) of 10.0% during the forecast period of 2024 to 2029.

Point-of-Care Diagnostics: Technologies and Global Markets

Published - Oct 2024 | Publisher - BCC Publishing | Code - HLC043H

The global market for point-of-care diagnostics was valued at $36.9 billion in 2023. It is expected to grow from $40.6 billion in 2024 to $65.9 billion by the end of 2029, at a compound annual growth rate (CAGR) of 10.2% from 2024 through 2029.

Recent Reports

Global DNA Sequencing: Research, Applied and Clinical Markets

Published - Dec 2024 | Publisher - BCC Publishing | Code - BIO045J

The global market for DNA sequencing is expected to grow from $14.8 billion in 2024 and is projected to reach $34.8 billion by the end of 2029, at a compound annual growth rate (CAGR) of 18.6% during the forecast period of 2024 to 2029.

Artificial Intelligence (AI) in Cancer

Published - Nov 2024 | Publisher - BCC Publishing | Code - BIO196B

The global market for artificial intelligence (AI) in cancer is estimated to increase from $2.2 billion in 2024 to reach $6.3 billion by 2029, at a compound annual growth rate (CAGR) of 23.1% from 2024 through 2029.

Cell and Gene Therapy Tools, and Reagents: Global Markets

Published - Nov 2024 | Publisher - BCC Publishing | Code - BIO208C

The global market for Cell and Gene Therapy (CGT) Tools and Reagents is estimated to increase from $10.0 billion in 2024 to reach $16.7 billion by 2029, at a compound annual growth rate (CAGR) of 10.8% from 2024 through 2029.

Single-use Technologies for Biopharmaceuticals: Global Markets

Published - Nov 2024 | Publisher - BCC Publishing | Code - BIO099F

The global market for single-use technologies for biopharmaceuticals is expected to grow from $6.5 billion in 2024 and is projected to reach $11.2 billion by the end of 2029, at a compound annual growth rate (CAGR) of 11.6% during the forecast period of 2024 to 2029.

Induced Pluripotent Stem Cells: Global Markets

Published - Nov 2024 | Publisher - BCC Publishing | Code - BIO135F

The global market for induced pluripotent stem cells (iPSCs) is expected to grow from $3.4 billion in 2023 to reach $5.2 billion by the end of 2028, at a compound annual growth rate (CAGR) of 9.1% from 2023 to 2028.

Top Trending Reports

Single-use Technologies for Biopharmaceuticals: Global Markets

Published - Nov 2024 | Publisher - BCC Publishing | Code - BIO099F

The global market for single-use technologies for biopharmaceuticals is expected to grow from $6.5 billion in 2024 and is projected to reach $11.2 billion by the end of 2029, at a compound annual growth rate (CAGR) of 11.6% during the forecast period of 2024 to 2029.

Cell and Gene Therapy Tools, and Reagents: Global Markets

Published - Nov 2024 | Publisher - BCC Publishing | Code - BIO208C

The global market for Cell and Gene Therapy (CGT) Tools and Reagents is estimated to increase from $10.0 billion in 2024 to reach $16.7 billion by 2029, at a compound annual growth rate (CAGR) of 10.8% from 2024 through 2029.

Global Market Opportunities and Competitive Landscape for CDMO

Published - Nov 2024 | Publisher - BCC Publishing | Code - PHM238B

The global CDMO market was valued at $128.0 billion in 2023. This market is expected to grow from $136.6 billion in 2024 to $191.6 billion by the end of 2029, at a compound annual growth rate (CAGR) of 7.0% from 2024 to 2029.

Chronic Disease Management: Therapeutics, Device Technologies and Global Markets

Published - Oct 2024 | Publisher - BCC Publishing | Code - HLC239C

The global market for chronic disease management therapeutics and device technologies was valued at $675.0 billion in 2023. It is projected to grow from $726.3 billion in 2024 to $1.1 trillion by 2029, at a compound annual growth rate (CAGR) of 8.1% from 2024 through 2029.

Medical Devices Industry: Competitive Landscape

Published - Nov 2024 | Publisher - BCC Publishing | Code - MDS010C

The global market for medical devices is estimated to increase from 810.4 billion in 2024 to reach $1.3 trillion by 2029, at a compound annual growth rate (CAGR) of 9.8% from 2024 through 2029.

Become A Member

BCC Research offers a comprehensive library of reports, granting members unlimited access to data, insights, and market intelligence for informed business decisions, while actively supporting members in their evolving journeys and prioritizing high-quality, relevant topics based on continuous engagement with the research community.

Find Out More

Custom Consulting

BCC Research emphasizes the importance of organizations leveraging highly customized market insights aligned with specific strategic business objectives through direct engagement with primary sources and proprietary forecasting models for profitable decision-making in maximizing growth opportunities and minimizing risks.

Customize Now

Scorecard

The Venture Scorecard provides commercialization offices and decision makers with expert analysis, offering strategic insights crucial for aligning objectives with market realities at various stages of commercializing new products or evaluating investment opportunities, from opportunity assessment to growth planning.

Find Out More

Innovation Spotlight

Our industry experts offer strategic guidance to maximize the market potential of commercialized products, patents, and IP by providing insights into market trends, competitive dynamics, and effective positioning, using the Innovation Spotlight service for enhanced exposure to thought leaders and the wider community.

Find Out More
Next-generation Sequencing: Emerging Clinical Applications and Global Markets
Sample Report