BEONCHIP

BE-Gradient is a device designed to apply electrochemical gradients to 3D cell cultures. BE-Gradient is compatible with optical microscopy (inverted phase contrast, confocal, fluorescence). BE-Gradient consists of a central chamber for cell culture and two lateral channels connecting to the central chamber through three small microchannels. Lateral channels are meant to simulate blood vessels. 2D culture is also possible for adherent cells in the central chamber and the lateral channels.

BE-Flow is an easy-to-use device suitable for cell culture under flow. It allows long-term 2D or 3D culture performance in two independent channels. BE-Flow is compatible with any microfluidic pump system and can be used simply with a rocker, thanks to its fluid reservoirs situated by the inlets/outlets. This is an optimal device for vascular research where shear stress plays a major role in gene expression.

BE-Transflow allows the study of complex culture configurations by joining a culture well with a microfluidic channel via a porous membrane. This device is optimal for Air Liquid Interface (ALI) culture, endothelium/epithelium barrier, and crosstalk studies.