Oligonucleotides: Global Markets

Report Code: BIO220C

Publish Date: Jan 2026

Publisher: BCC Publishing

Category: Cell Biology

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Report Highlights

The global market for oligonucleotides was valued at $9.1 billion in 2025 and is estimated to reach $15.7 billion by 2030, at a compound annual growth rate (CAGR) of 11.5% from 2025 through 2030.

Report Includes

  • 64 data tables and 55 additional tables
  • In-depth analysis of the global oligonucleotides market
  • Analyses of the global market trends, with historic revenue (sales data) from 2022 to 2024, estimates for 2025 and projections of CAGRs through 2030
  • Estimates of the current market size and revenue prospects for the global oligonucleotide synthesis market, accompanied by a market share analysis by product, application and region
  • Facts and figures pertaining to the global market dynamics, opportunities and deterrents, technological advancements, regulations, prospects and the impact of macroeconomic factors
  • Insights derived from Porter’s Five Forces model, as well as global supply chain analyses
  • Patent review, featuring key granted and published patents
  • Analysis of the industry structure, including companies’ market shares and rankings, product mappings, strategic initiatives, M&A activity and a venture funding outlook
  • Overview of sustainability trends and ESG developments, with emphasis on consumer attitudes, as well as the ESG risk ratings and practices of leading companies
  • Company profiles of major players within the industry, including Alnylam Pharmaceuticals Inc., Biogen/Ionis Pharmaceuticals Inc., Novartis AG, and Sarepta Therapeutics Inc.

Report Scope

The report provides an overview of the oligonucleotides market and analyzes market trends. It includes global revenue ($ Million) for the base year 2024, estimated data for 2025 and forecast data from 2026 through 2030. The market is segmented by product type, application and region.

By product type, the market is segmented into oligonucleotide drugs, synthesized oligos, equipment and reagents, and services. The application segment is characterized by research and therapeutics and diagnostics. The report also includes an overview of the regulatory landscape for oligonucleotides.

The report also focuses on the regional segmentation of the market. The regions covered in this study include North America, Europe, the Asia-Pacific and the rest of the world (RoW), with a focus on major countries in these regions.

The report focuses on the major driving trends and challenges affecting the market and vendor landscape. It analyzes environmental, social and governance (ESG) developments and discusses emerging technologies related to the market. The report concludes with an analysis of the competitive landscape and industry structure. It also includes a dedicated section of company profiles, detailing leading market companies.

Report Synopsis

Report Metrics Details
Base year considered 2024
Forecast period considered 2025-2030
Base year market size $8.2 billion
Market size forecast $15.7 billion
Growth rate CAGR of 11.5% for the forecast period of 2025-2030
Units considered $ Millions
Segments covered Product Type, Application, Region
Regions covered North America, Europe, Asia-Pacific, Rest of the World
Countries covered U.S., Canada, Mexico, U.K., France, Germany, Italy, Spain, China, India, Japan, South Korea, Australia, South America, Middle East and Africa
Key Market Drivers
  • Growing Focus on Personalized Medicine
  • Increasing Use of Synthesized Oligos in Therapeutic Applications
  • Rising Prevalence of Rare Diseases
Companies studied
AGILENT TECHNOLOGIES INC.AJINOMOTO BIO-PHARMA
ALNYLAM PHARMACEUTICALS INC.ASTELLAS PHARMA INC.
BIOGENCHARLES RIVER LABORATORIES
EUROFINS GENOMICSGENSCRIPT
INTEGRATED DNA TECHNOLOGIES INC.MERCK KGAA
NOVARTIS AGNOVO NORDISK A/S
REVVITYSAREPTA THERAPEUTICS INC.
THERMO FISHER SCIENTIFIC INC.
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Frequently Asked Questions (FAQs)

The global oligonucleotides market was valued at $8.2 billion in 2024 and is expected to reach $15.7 billion by the end of 2030 at a CAGR of 11.5%.
  • Growing prevalence of rare diseases.
  • The increasing need for precision medicine.
  • Key challenges include - Complexities associated with oligos manufacturing, the High treatment costs, Product withdrawals and clinical trial failures
  • Key opportunities include - Exploring new application areas, DNA nanotechnology for drug delivery
The market has been segmented based on product type, application, and region.
Oligonucleotide therapeutics segment will dominate the oligonucleotides market. The growing understanding of the role of RNA in various disease conditions is driving research on RNA-based therapeutics. The growing number of product launches from companies such as Alnylam Pharmaceuticals and Sarepta Therapeutics, based on ASO and siRNA types, is a key factor contributing to their high market share.
North America accounted for 40.7% share of the market in 2024. North America has the presence of major players such as Alnylam Pharmaceuticals, Ionis Pharmaceuticals, and Sarepta Therapeutics which have many approved products. The other key factors that drive growth in the North American market, including the FDA's approval processes for rare disease therapeutics and continued funding from the National Institutes of Health (NIH) for advanced technologies.

Analyst Credentials

BCC Research Team possesses expertise and experience in life and physical science domains. They specialize in offering valuable business insights, including industry analysis, competitor intelligence, strategic and financial analysis, and opportunity assessment. The team has in-depth knowledge of various sectors, including healthcare, biotechnology, pharmaceuticals, IT, automation, advanced materials, and energy. They are proficient in qualitative and quantitative market intelligence providing clients with actionable insights. With a vast understanding of the competitive landscape, the team can support clients in making data-driven decisions to help them achieve a competitive edge in their respective markets.

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Table of Contents

All reports provided in PDF format. For shared licensing options (5+ Users), please call a representative at (+1) 781-489-7301 or contact us at info@bccresearch.com
Title/Chapter NamePagesMember Price
Full Report: Oligonucleotides: Global Markets125Free
Chapter- 1: Executive Summary5Free
Chapter- 2: Market Overview9Free
Chapter- 3: Market Dynamics8Free
Chapter- 4: Regulatory Landscape4Free
Chapter- 5: Emerging Technologies5Free
Chapter- 6: Market Segmentation Analysis35Free
Chapter- 7: Competitive Intelligence6Free
Chapter- 8: Sustainability in the Global Oligonucleotides Market: An ESG Perspective3Free
Chapter- 9: Appendix50Free

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This is an Excel-only version of the report.

Report Includes

    Total Number of Tables in this Report: 119

  • Summary Table: Global Market for Oligonucleotides, by Region, Through 2030
  • Table 1: FDA-Approved ASOs
  • Table 2: RNAi-Approved Drug List
  • Table 3: List of Approved Oligonucleotide Therapeutics, 2025
  • Table 4: List of Selected Pipeline Oligonucleotide Molecules
  • Table 5: Global Market for Oligonucleotides, by Product Type, Through 2030
  • Table 6: Global Market for Oligonucleotide Drugs, by Region, Through 2030
  • Table 7: Global Market for Synthesized Oligos, by Region, Through 2030
  • Table 8: Global Market for Oligonucleotide Equipment and Reagents, by Region, Through 2030
  • Table 9: Global Market for Oligonucleotide Services, by Region, Through 2030
  • Table 10: Global Market for Oligonucleotide, by Application, Through 2030
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Report Highlights

The global market for oligonucleotides is expected to grow from $7.0 billion in 2023 and projected to reach $11.7 billion by the end of 2028, at a compound annual growth rate (CAGR) of 11.0% during the forecast period of 2023 to 2028.

Report Includes

  • 31 data tables and 48 additional tables
  • Overview and an analysis of the global markets for oligonucleotides
  • Analyses of the global market trends, with historical market revenue data (sales figures) from 2020 to 2022, estimates for 2023, and projections of compound annual growth rates (CAGRs) through 2028
  • A discussion of the current and future market potential of oligonucleotide synthesis, as well as the competitive landscape, market dynamics, ongoing research, and trends in market growth
  • Estimate of the market size and revenue forecasts, and a corresponding market share analysis based on product type, application and region
  • Coverage of the total market for oligonucleotide synthesis, which includes RNA oligos, DNA oligos, and the platform services offered by many companies
  • Overview of the sustainability trends and ESG developments, with an emphasis on consumer attitudes, ESG score analysis, and the ESG practices followed by leading companies
  • A look at the recent developments in the market and emerging technologies
  • An analysis of the key patents and recent clinical trials on oligonucleotide synthesis-based products and applications
  • Competitive intelligence, including the major vendors’ market shares, recent M&A activity, and venture funding outlook
  • Profiles of the leading global players, including Thermo Fisher Scientific Inc., Agilent Technologies, Inc., Integrated DNA Technologies, Inc., Eurofins Scientific, and Biolytic Lab Performance Inc.
Published - Sep-2021| Analyst - BCC Publishing| Code - BIO220A

Report Highlights

The global market for oligonucleotide synthesis should grow from $6.1 billion in 2021 to $10.2 billion by 2026 with a compound annual growth rate (CAGR) of 10.7% for the period of 2021-2026.

Report Includes

  • 22 data tables and 20 additional tables
  • An overview of the global market for oligonucleotides
  • Estimation of the market size and analyses of global market trends, with data from 2019, 2020, estimates for 2021 and projections of compound annual growth rates (CAGRs) through 2026
  • Evaluation of current market trends, and technological advancements within the industry and market share analysis of oligonucleotides by type, application, and region
  • Information on the classifications and applications of oligonucleotides and detailed description of DNA oligos and RNA oligos synthesis
  • Details of solid phase chemical synthesis and alternative forms of oligonucleotide synthesis processes and insights into government regulations for oligonucleotide-based drugs
  • Information on CRISPR-Cas diagnosis and therapeutic tools for SARS-CoV-2 infection, and discussion on ASO as a COVID-19 therapeutic
  • A look at the new product developments, clinical trials, patents, mergers and acquisitions and collaborations or partnership of the industry
  • Company profiles of major players of the industry, including Agilent Technologies , Eurofins Scientific, Biolegio, Merck KGaA , Integrated DNA Technologies and Thermo Fisher Scientific

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Oligonucleotides: Global Markets
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