Protein Expression: Global Markets

Report Code: BIO165B

Publish Date: Nov 2025

Publisher: BCC Publishing

Category: Cell Biology

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Report Highlights

The global market for protein expression is estimated to grow from $4.7 billion in 2025 to reach $7.9 billion by 2030, at a compound annual growth rate (CAGR) of 10.9% from 2025 through 2030.

Report Includes

  • 52 data tables and 65 additional tables
  • An overview of the global market for protein expression
  • In-depth analysis of global market trends, featuring historical revenue data for 2022–2024, estimated figures for 2025, as well as forecasts for 2030. This analysis includes projections of compound annual growth rates (CAGRs) through 2030
  • Evaluation of the current market size and revenue growth prospects specific to the protein expression, accompanied by a market share analysis by system type, product, application, end user and region
  • Analysis of current and future demand in the global protein expression, along with a detailed analysis of the competitive environment, market regulations and reimbursement practices
  • Analysis of drivers, challenges and opportunities affecting market growth
  • Coverage of evolving technologies, the current and future market potential, R&D activities, growth strategies, new product pipeline, regulatory framework and reimbursement scenarios, and ESG trends of the market
  • Market share analysis of the key market participants in the protein expression industry, along with their research priorities, product portfolios, global rankings and competitive landscape
  • Profiles of the major companies, including Thermo Fisher Scientific Inc., Bio-Rad Laboratories Inc., Merck KGaA, Sartorius AG and Agilent Technologies Inc.

Report Scope

The report provides an overview of the global protein expression market and analyzes key market trends. Global revenue ($ million) for the base year 2024 and estimated data for the forecast period, 2025 through 2030, are also included. The market is segmented into expression system, product types, application, end user and regions. The regions covered in this study are North America, Europe, Asia-Pacific (APAC) and the Rest of the World (RoW), with a focus on major countries in these regions.

The report examines trends and challenges that affect the market and vendor landscape; analyzes environmental, social and corporate governance (ESG) developments; and discusses emerging technologies related to the market.

The report concludes with an analysis of the competitive landscape, providing rankings and market shares of key companies in the global protein expression market. A dedicated section of company profiles provides an overview, key financials, product portfolios and recent developments of leading companies, including a patent analysis.

Report Synopsis

Report Metrics Details
Base year considered 2024
Forecast period considered 2025-2030
Base year market size $4.3 Billion
Market size forecast $7.9 Billion
Growth rate CAGR of 10.9% from 2025 to 2030
Units considered $ Millions
Segments covered By System Type, Product, Application, End User and Region
Regions covered North America, Europe, Asia-Pacific (APAC) and the Rest of the World (RoW)
Key Market Drivers
  • Demand for therapeutic proteins and biologics.
  • Investments in biopharmaceuticals.
  • Technological advances in protein expression.
  • Demand for biopharmaceuticals in emerging countries.
  • Broad applications for CRISPR technology.
Companies studied
AGILENT TECHNOLOGIES INC.BIO-RAD LABORATORIES INC.
CORNING INC.DANAHER CORP.
FUJIFILM CELLULAR DYNAMICS INC.GENSCRIPT
LONZAMERCK KGAA
NEW ENGLAND BIOLABSORIGENE TECHNOLOGIES INC.
PROMEGA CORP.PROTEOGENIX INC.
QIAGENSARTORIUS AG
THERMO FISHER SCIENTIFIC INC.
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Frequently Asked Questions (FAQs)

The estimated market size of the protein expression systems is $7.9 billion by the end of 2030. The CAGR is 10.9%.
Key drivers include:
  • Growing demand for therapeutic proteins and biologics.
  • Investments in biopharmaceuticals.
  • Technological advances in protein expression.
Key challenges include:
  • Complexities in government regulations and policies.
  • High cost of protein drugs
Key opportunities include:
  • Demand for biopharmaceuticals in emerging countries.
  • Expanding applications for CRISPR technology.
By expression system, by product type, by application, by end-user and region.
The protein expression market was dominated by mammalian cell expression systems, particularly mammalian cells like CHO cells, which are favored for manufacturing complex therapeutic proteins with the appropriate folding and post-translational modifications.
North America is a leading region in terms of revenue contribution to the global market. North America plays a crucial role in the global protein expression market, driven by the growing demand in the region for therapeutic proteins and the expanding use of biologics, including monoclonal antibodies (mAbs) and cell and gene therapies.

Analyst Credentials

BCC Research Team possesses expertise and experience in life and physical science domains. They specialize in offering valuable business insights, including industry analysis, competitor intelligence, strategic and financial analysis, and opportunity assessment. The team has in-depth knowledge of various sectors, including healthcare, biotechnology, pharmaceuticals, IT, automation, advanced materials, and energy. They are proficient in qualitative and quantitative market intelligence providing clients with actionable insights. With a vast understanding of the competitive landscape, the team can support clients in making data-driven decisions to help them achieve a competitive edge in their respective markets.

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Table of Contents

All reports provided in PDF format. For shared licensing options (5+ Users), please call a representative at (+1) 781-489-7301 or contact us at info@bccresearch.com
Title/Chapter NamePagesMember Price
Full Report: Protein Expression: Global Markets157Free
Chapter- 1: Executive Summary5Free
Chapter- 2: Market Overview17Free
Chapter- 3: Market Dynamics7Free
Chapter- 4: Regulatory Landscape3Free
Chapter- 5: Emerging Technologies and New Developments2Free
Chapter- 6: Market Segmentation Analysis54Free
Chapter- 7: Competitive Intelligence6Free
Chapter- 8: Sustainability in the Protein Expression Market: ESG Perspective6Free
Chapter- 9: Patent Landscape9Free
Chapter- 10: Appendix48Free

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This is an Excel-only version of the report.

Report Includes

    Total Number of Tables in this Report: 117

  • Summary Table: Global Market for Protein Expression, by Region, Through 2030
  • Table 1: Advantages and Disadvantages of Protein Expression Systems
  • Table 2: Prokaryotes vs. Eukaryotes Protein Synthesis
  • Table 3: Comparison of Expression Systems
  • Table 4: Asia-Pacific Regulatory Landscape
  • Table 5: RoW Regulatory Landscape
  • Table 6: Comparison of Protein Expression Systems and Their Respective Advantages and Disadvantages
  • Table 7: Advantages, Challenges and Most Common Applications of Protein Expression Systems
  • Table 8: Global Market for Protein Expression, by Type, Through 2030
  • Table 9: Global Market for Prokaryotic Expression Systems, by Region, Through 2030
  • Table 10: Global Market for Mammalian Cell Expression Systems, by Region, Through 2030
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Report Highlights

The global market for protein expression should grow from $1.8 billion in 2017 to $3.1 billion by 2022 at a compound annual growth rate (CAGR) of 11.3% from 2017 through 2022.

Report Includes

  • 45 data tables 34 additional tables
  • An overview and in-depth analysis of the global markets for protein expression technologies
  • Analyses of global market trends with data from 2016 and 2017, and projections of compound annual growth rates (CAGRs) through 2022
  • Discussion on perfusion approaches and supporting practices such as continuous bio manufacturing, and digital and model-based controls
  • Identification of key market dynamics and the factors impacting the global market for protein expression and its sub-segments
  • Regional dynamics of the global protein expression market and analysis of trends and opportunities in major regions covering North America, Europe, Asia-Pacific and the rest of the world (ROW)
  • A relevant patent analysis focuses on describing technological trends across periods of time and regions, such as the U.S., Europe and Japan
  • Detailed analysis of the cloning technologies, production of recombinant proteins and problems associated with protein production
  • Assessment of major stakeholders, product portfolios and recent developments and the competitive landscape among market leaders
  • Company profiles of leading global payers, including Agilent Technologies, Bio-Rad Laboratories Inc., Merck KGaA, Promega Corp., GenScript, Thermo Fisher Scientific Inc., and Qiagen N.V.

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Protein Expression: Global Markets
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