March 30, 2016
Wellesley, Mass., March 30, 2016 – Electrophoresis has been a principal driving force behind advancements in proteomics research. BCC Research reveals in its new report that technology enhancement methods like 2D fluorescence difference gel electrophoresis (2D DIGE) hold promising protein detection.
Electrophoresis is an analytical separation technique that allows the migration of charged particles under the influence of an electric field, based on their charge-to-mass ratio. The electrophoresis market is broadly segmented into gel electrophoresis (GE) and capillary electrophoresis (CE) technologies.
The global market should reach $2.3 billion in 2020 from $1.6 billion in 2015, reflecting a five-year compound annual growth rate (CAGR) of 6.5%. The GE segment accounted for 61.3% of the total electrophoresis market ($949.5 million) in 2014 and 60.7% ($1 billion) in 2015. The presence of a high installed base for these systems is likely to influence a modest growth with an estimated five-year CAGR of 5.5%. CE technology continues to make inroads in the separation market with estimated revenues of $951.2 million in 2020, demonstrating at five-year CAGR of 8%.
The technology developments in the gel imaging segment are accompanied by corresponding progress seen in gel informatics. Informatics vendors are taking many initiatives to address the growing concern of reproducibility in the 2D gel technique by sophisticated signal analysis algorithms that reflect true biological outcomes. Gel informatics is likely to witness the highest growth compared to the other product segments during the forecast period.
Although electrophoresis is a standardized technique, there have been considerable technology advances because of its ever-expanding research applications. Among the major GE techniques, the polyacrylamide gel (2D PAGE) technique has received immense attention, fueled by the growing field of proteomics. 2D PAGE has a high resolving power to separate posttranslational protein entities. There have been significant technology developments in different product segments such as informatics and gel imaging.
2D PAGE in particular, has seen continual product innovation both in the aftermarket and postelectrophoretic analysis segments. Because proteomics investments have not been very rewarding, a clear need exists for refinement of analytical tools and techniques. The development of supporting labeling and staining methods is expected to increase confidence in proteomics research analysis. A striking example of technology enhancement is the 2D DIGE. This method, which provides a higher accuracy of quantitative data with minimal occurrence of false positives, has been a principal driving force behind advancements in proteomics research.
“2D DIGE is one of the technology-enhancement methods gaining considerable significance in the electrophoresis market,” says BCC Research analyst Lance Leverette. “By tagging the protein samples with fluorescent dyes, subtle variations in protein abundances between the two samples can be sharply detected. The resulting fluorescent images are superimposed to monitor changes in protein expression and enable spot detection with higher accuracy levels in gel quantitation than 2D PAGE. This technology is driving niche market participants to develop reagents tailored for this method.”
Electrophoresis Technology: Global Markets (MST040D) analyzes the industry by technology, by type, and by end-user application. The report examines emerging applications, trends, pricing considerations, R&D, government regulations, and competitive technologies. Analyses of global market drivers and trends, with data from 2014, 2015, and projections of CAGRs through 2020 also are provided.
Editors and reporters who wish to speak with the analyst should contact Steven Cumming at steven.cumming@bccresearch.com.
Electrophoresis Technology: Global Markets( MST040D )
Publish Date: Mar 2016
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